What to Know
Symptoms of Methanol Poisoning
Methanol poisoning can be difficult to recognise initially because symptoms may be delayed for 12–24 hours and can resemble ordinary alcohol intoxication. Early symptoms include nausea, vomiting, headache, dizziness, abdominal pain and general weakness, and some people may initially feel relatively well.
As toxic formic acid accumulates, more characteristic features of methanol poisoning develop. Symptoms include visual disturbances, ranging from blurred or altered vision to blindness, severe abdominal pain, vomiting, fast or laboured breathing, confusion and increasing drowsiness. In severe cases, unconsciousness, seizures, coma and death can occur.
The severity of symptoms depend on the amount of methanol consumed and how quickly treatment begins. Suspected methanol poisoning is a medical emergency, even if symptoms initially appear mild.
Diagnosis and treatment of Methanol Poisoning
Diagnosis of methanol poisoning is established with blood tests, including methanol concentration and other biochemical tests. However, treatment may need to begin based on the exposure history and clinical features rather than waiting for laboratory confirmation, because deterioration can occur rapidly.
Treatment aims to prevent methanol being converted into toxic formic acid, correct the imbalance and removing methanol and formic acid from the body. There are antidotes that inhibit methanol metabolism, medications that promote formate metabolism, and haemodialysis for efficient removal of methanol and formic acid in severe cases.
Early treatment is critical and can substantially reduce the risk of death, blindness and permanent neurological injury. Anyone who may have consumed methanol-contaminated alcohol and develops symptoms should go to the nearest emergency department immediately.
Prevention of Methanol Poisoning
Methanol cannot be reliably identified by taste, smell or appearance, so the safest approach is to avoid alcohol of uncertain origin. Alcohol from licensed, established retailers is generally less likely to be contaminated than homemade, informally distilled or counterfeit products. Choose bottles with an intact, factory-sealed cap and unbroken tamper-evident seal, and do not drink from any bottle that appears opened, resealed or tampered with.
Travellers are advised to avoid unlabelled or poorly labelled spirits, unusually cheap alcohol, free shots, homemade or locally distilled drinks, and cocktails served in large open containers such as jugs or buckets. Counterfeit spirits can appear genuine, so even apparently branded products are not completely risk-free. Australian travellers should remain aware of methanol poisoning wherever unregulated or informally produced alcohol is consumed.