What to Know
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Typhoid symptoms
After an incubation period of five to 21 days, symptoms of fever, fatigue and abdominal pain begin. This may be accompanied by constipation or, in some cases, diarrhoea. In the third week of illness, in a few cases the infection can be complicated by perforation of the intestine.
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Typhoid diagnosis and treatment
The infection is diagnosed by isolating the Salmonella Typhi strain of bacteria from blood samples in the laboratory. With effective antibiotic therapy, the vast majority of people recover in the following weeks to months.
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Typhoid prevention
Prevention of typhoid fever involves adhering to good food and water hygiene measures while overseas and vaccination for those aged more than two years old. Typhoid immunisation is not part of the routine childhood vaccination schedule in Australia, so most people don’t consider having it until travelling overseas. Two options are available: an injectable vaccination can be used for anyone over the age of two; and a three or four-dose oral vaccine can be given in those over six years old. A combination vaccine which includes both typhoid and hepatitis A immunisation is available.
Adverse effects of typhoid vaccination are usually mild and short-lived. After the injectable vaccine, pain and redness at the injection site can occur in 10 to 20% of people. Around 3% of people experience fever and nausea. Gastrointestinal upset can occur after the oral vaccine, as can a transient rash. Typhoid vaccines, injectable and oral, are associated with very few serious adverse events. Severe allergic reactions are very rare.
Typhoid immunisation prior to travel provides protection for three years for the injectable and three-dose oral immunisations.