What to Know
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Rabies symptoms
After an incubation period which is usually one to three months (but can range from a few days to several years), initial symptoms can include fever, fatigue, muscle aches, nausea and vomiting. In the most common form of the illness, known as encephalitic rabies, the illness progresses after a few days to a week and can include hyperactivity, painful spasms of the throat when swallowing and ‘hydrophobia’, a fear of water. These symptoms then give way to coma and death in almost all cases.
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Rabies diagnosis and treatment
The diagnosis is usually suspected based on an illness with characteristic symptoms taking place after an animal bite. This is then confirmed with laboratory tests like PCR testing of saliva and skin samples, and antibody testing of blood and spinal fluid.
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Rabies prevention
A rabies vaccine is available. This is commonly given in a two-dose schedule prior to travel to a rabies endemic area for those at risk.
The decision of whether or not to have rabies vaccination prior to travel needs to take into account the duration of the trip, the degree of animal contact anticipated and the availability of appropriate therapy for animal bite wounds in the region of travel. Adult travellers to areas where adequate medical facilities are available who will not be working with animals may not require it, but it is best to discuss this with your travel doctor. Whether or not rabies immunisation is undertaken, avoidance of dogs, cats, monkeys and other wildlife is a sensible precaution.
As there is no proven effective treatment for rabies once symptoms have developed, it is vital to seek preventive medical therapy for an animal bite which occurs in an affected country. This includes first aid, cleaning of the bite wound (for at least 15 minutes with soap and water) and rabies immunisation. Immunisation after a significant animal exposure is required even for those who have received the rabies vaccine prior to travel.