What to Know
Leptospirosis symptoms
Leptospirosis symptoms typically appear between 2 and 30 days after exposure, although most cases begin within 5 to 14 days. Illness can vary widely in severity, ranging from a mild flu-like illness to severe, life-threatening disease involving multiple organs.
In the early phase, symptoms are often non-specific and can easily be mistaken for other infections such as influenza or dengue. This stage commonly includes sudden fever, chills, severe headache, and muscle pain, particularly in the calves, thighs, and lower back. Other symptoms include fatigue, nausea, vomiting, and sometimes diarrhoea. Some people also develop red or bloodshot eyes, which can be a useful clinical clue.
In a smaller proportion of cases, the illness progresses to a more severe form involving yellowing of the skin and eyes, kidney impairment, liver inflammation, bleeding problems, chest pain, cough, and shortness of breath. Severe infection may also affect the brain, leading to confusion and other symptoms. Without treatment, leptospirosis can become a medical emergency.
Leptospirosis diagnosis and treatment
Doctors diagnose leptospirosis by combining your symptoms, travel history, and blood or urine tests. Because early symptoms often look like a regular viral illness such as flu, it is important to tell your doctor if you have recently travelled to a higher-risk country or had contact with freshwater, flooding, or animals.
Treatment involves antibiotics, which work best when started early in the illness. If the infection is mild, antibiotic tablets may be enough. These help clear the bacteria from the body and reduce the risk of the illness becoming more serious.
If the infection is more severe, treatment is usually given in hospital. This is because stronger antibiotics are needed intravenously through a drip, along with close monitoring. Patients may also receive fluids to prevent dehydration, regular blood tests to check kidney and liver function, and breathing support if the lungs are affected. Early medical care greatly improves recovery and reduces the risk of complications.
Leptospirosis prevention
Prevention of leptospirosis is focused on avoiding exposure to contaminated water, soil, and animal urine. Travellers should avoid swimming, wading, or rafting in freshwater rivers, lakes, or floodwater in regions where leptospirosis is known or outbreaks have been reported. Even water that appears clean can carry the bacteria, particularly after heavy rainfall or flooding events.
Protective clothing plays an important role in reducing risk during outdoor activities. Wearing closed footwear and long trousers helps prevent bacteria entering through small cuts or abrasions. Any breaks in the skin should be covered with waterproof dressings, especially when hiking or working in rural or wet environments. Hand hygiene is also important, particularly after contact with soil, animals, or outdoor water sources.
Travellers should also be aware that rodents are a key reservoir of infection globally, so environments with visible rodent activity or poor sanitation carry higher risk. Food and drink hygiene, while not the primary route of transmission, still supports overall infection prevention in higher-risk settings.
There is no routine vaccine available for Australian travellers, so prevention relies entirely on behavioural precautions and environmental awareness. For those undertaking high-risk occupational or adventure activities in endemic regions, personalised advice from a travel health professional is recommended before departure.